Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

We are proud to announce that in a collaboration with the UCSD Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, we have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

Full Article may be found on the October 9 issue of Nature Materials. PDF Full Text.

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Stem Cells Regenerate Human Lens After Cataract Surgery, Restoring Vision

Approach may have broad therapeutic implications on tissue and organ repair

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

The treatment, which has been tested in animals and in a small, human clinical trial, produced much fewer surgical complications than the current standard-of-care and resulted in regenerated lenses with superior visual function in all 12 of the pediatric cataract patients who received the new surgery.

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Rapid noninvasive fetal screening

Dr. Zhang has published a study to develop a more rapid and safe method of diagnosing fetal chromosomal aneuploidies, such as Down syndrome. You can download a PDF of the full article. Click here for news coverage and an audio clip.

Dr. Zhang named AAAS Fellow

Dr. Zhang was named a Fellow of the American Association for the Advancement of Science (AAAS). Fellows are honored for their “efforts toward advancing science applications that are deemed scientifically or socially distinguished.” The AAAS also publishes the journal Science.

Read the full press release here.

Dr. Zhang receives NIH Director’s Transformative R01 Award

“Zhang and co-principal investigators Sheng Ding, PhD, from The Scripps Research Institute, and Thomas Reh, PhD from the University of Washington, received the highest possible scores for their proposal to investigate the regenerative potential of retinal cells.  Their long-term goal is to restore visual function lost through diseases such as macular degeneration and retinitis pigmentosa.”

Read the full press release here.